Computational Comparative Genomics of Eu- and Prokaryotes

Computational Comparative Genomics of Eu- and Prokaryotes

With the rapid advent of worldwide genome projects, scientists are confronted with a tremendous increase in the amount of novel information. However, the gap between data collection and interpretation is also growing. For this reason, genome databases contain a wealth of information which is accessible, but which may remain obscured. Much can be learned from comparing different genomes, as geno...

Comparative genomics and the evolution of prokaryotes.

Although biologists have long recognized the importance of studying evolution to understand the organization of living organisms, only with the development of genomics have evolutionary studies become part of their routine toolkit. Placing genomes into an evolutionary framework has proved useful for understanding the functioning of organisms. It has also substantially increased understanding of...

Computational Comparative Genomics : Genes , Regulation ,

Comparative and Computational Methods for Microbial Genomics

Title of Dissertation: COMPARATIVE AND COMPUTATIONAL METHODS FOR MICROBIAL GENOMICS Derrick Edward Wood, Doctor of Philosophy, 2014 Directed by: Professor Steven L. Salzberg Department of Computer Science Through the study of genomic sequences, researchers are able to learn much about the workings of life. As sequencing technology has improved over the past decade, the number of genomes that ha...

VISTA: computational tools for comparative genomics

Comparison of DNA sequences from different species is a fundamental method for identifying functional elements in genomes. Here, we describe the VISTA family of tools created to assist biologists in carrying out this task. Our first VISTA server at http://www-gsd.lbl.gov/vista/ was launched in the summer of 2000 and was designed to align long genomic sequences and visualize these alignments wit...